TIKOSYN is a medicine that has been used for more than 10 years. It has a proven method of safe use in patients at risk for a type of abnormal heartbeat.
Cimetidine (Tagamet®, Tagamet HB®)
Verapamil (Calan®, Calan SR®, Covera-HS®, Isoptin®,
Verelan®, Verelan PM®, Tarka®)
Ketoconazole (Nizoral®, Xolegel®, Extina®)
Trimethoprim alone (Proloprim®, Trimpex®) or the combination
and sulfamethoxazole (Bactrim®, Septra®, Sulfatrim®)
Prochlorperazine (Compazine®, Compro®)
Hydrochlorothiazide alone or in combination with other medicines (such as Esidrix®,
Ezide®, Hydrodiuril®, Hydro-Par®, Microzide®, or Oretic®)
Ask your doctor if you are not sure if any of your medicines are the kind listed above.
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If you have questions about TIKOSYN, there are a number of things you can do:
Call your doctor and go to the hospital right away if you:
Like other medicines, TIKOSYN can cause side effects. These include the dangerous abnormal rhythm mentioned above, as well as others.
The most common side effects of TIKOSYN include:
Call your doctor right away if you have signs of electrolyte imbalance:
TIKOSYN can cause other side effects. Tell your doctor if you have any side effects that bother you or do not go away. For more information, ask your doctor or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
You must take TIKOSYN (dofetilide) exactly as your doctor tells you to. After your hospital stay, you will know what your personal TIKOSYN dose is. Then, it’s important you take that dose every day. Your doctor will tell you more about the best time of day to take TIKOSYN.
Tell your doctor about all of your medical conditions, including if you:
Tell your doctor especially if you take medicines to treat:
TIKOSYN and other medicines may affect each other. This can cause serious side effects.
Ask your doctor if you are not sure about the medicines you take. Tell your doctor about all:
Know the medicines you take. Keep a list of them. Show it to your doctor and pharmacist when you get a new medicine. And, tell all of your doctors that you are taking TIKOSYN.
Your TIKOSYN is just to treat your atrial fibrillation/atrial flutter (AF/AFL).