Frequently Asked Questions
Although your doctor is the best source for answering your specific questions about irregular heartbeats, atrial fibrillation, atrial flutter, and treatment with TIKOSYN, you can find answers to common questions here.
General Information About TIKOSYNTop
What is TIKOSYN?
TIKOSYN is a prescription medicine. It affects the rhythm of your heart. It is used to treat irregular heartbeats such as atrial fibrillation (AF) and atrial flutter (AFL). It's only suited for patients who have lots of symptoms. TIKOSYN can be used to help your heart beat normally again and/or to help keep it beating that way.
It is not known if TIKOSYN is safe and effective in children under 18 years of age.
What is the most important information I should know about TIKOSYN?
TIKOSYN can cause serious side effects, including a type of abnormal heartbeat called Torsade de Pointes, which can lead to death.
To establish the right dose of TIKOSYN, treatment with TIKOSYN must be started in a hospital where your heart rate and kidney function will be checked for the first 3 days of treatment. It is important that when you go home, you take the exact dose of TIKOSYN that your doctor prescribed for you.
While you take TIKOSYN, always watch for signs of abnormal heartbeat.
Call your doctor and go to the hospital right away if you:
- feel faint
- become dizzy, or
- have a fast heartbeat
How to Get Brand-Name TIKOSYNTop
How can I ensure that I won’t get switched to a generic substitute?
Here are 3 suggested tips to help make sure you receive brand-name TIKOSYN and not a generic:
- At your doctor’s office: Ask your doctor to prescribe brand-name TIKOSYN and to indicate “DAW” (Dispense As Written)—or the language used in your state—on all of your TIKOSYN prescriptions.
- At your pharmacy’s drop-off: Tell the pharmacist that you want brand-name TIKOSYN—and be sure to use the TIKOSYN Savings Card. The TIKOSYN Savings Card can only be used with brand-name TIKOSYN.
- At your pharmacy’s pick-up: Check your pills to be sure they’re brand-name TIKOSYN—not the generic—and also check that you’ve saved on your prescription.
What should I do if I receive a generic substitute instead of brand-name TIKOSYN?
Talk to your doctor and/or your pharmacist to ask if you should be getting brand-name TIKOSYN.
How do I know if I received brand-name TIKOSYN?
Check your pills for the distinctive shape and markings of brand-name TIKOSYN.
Saving on TIKOSYNTop
What is the TIKOSYN Savings Card?
The TIKOSYN Savings Card allows eligible patients to pay as little as $4 every time they get a 30-day fill of brand-name TIKOSYN—and could save up to $3,000 a year. If you have a prescription for brand-name TIKOSYN, you can use the card for every fill through December 31, 2020.*
How do I use the TIKOSYN Savings Card?
There are 2 ways to use the card immediately. Once you’ve activated your Savings Card, you can either:
- Bring a printed copy of it to the pharmacy
- Show it to your pharmacist on your phone
You can keep this card with you and continue to save on each fill for TIKOSYN through December 31, 2020.
Who is eligible to use the TIKOSYN Savings Card?
To be eligible to use a TIKOSYN Savings Card, you must:
- Be 18 years of age or older
- Not be a resident of Massachusetts (Restrictions may apply for other states)
- Not be covered by Medicare, Medicaid, or any other federal or state healthcare programs
The Card is not valid for California residents whose prescriptions are covered in whole or in part by third-party insurance, a healthcare service plan, or other health coverage where a lower cost generic is available, unless applicable step therapy or prior authorization requirements have been completed.
Please check with your healthcare professional or insurer to confirm eligibility.
To learn the full details of who is eligible, please see the full Terms and Conditions.
How do I get a TIKOSYN Savings Card?
To get a Savings Card, register here and then download your card or have it sent to you via mail or email.
If I already have a TIKOSYN Savings Card, how can I activate it?
You can activate your Savings Card here.
Where can I use the TIKOSYN Savings Card?
You can use the Savings Card at any participating pharmacy. Use the Pharmacy Finder to locate a pharmacy near you that has recently accepted the TIKOSYN Savings Card.
Can I use the TIKOSYN Savings Card on a previously filled prescription?
The TIKOSYN Savings Card can only be used for new prescriptions that are filled after you have activated the card.
Does the TIKOSYN Savings Card work through mail-order pharmacies?
For reimbursement when using a nonparticipating pharmacy/mail order: Pay for your TIKOSYN prescription and mail copy of original pharmacy receipt (cash register receipt NOT valid) with product name, date, and amount circled to: Pfizer, ATTN: TIKOSYN, PO Box 4930, Warren, NJ 07059-6600. Be sure to include a copy of the front of your TIKOSYN Savings Card, your name, and mailing address. Please expect up to 4 to 6 weeks for reimbursement.
What should I tell my doctor before taking TIKOSYN?
Before taking TIKOSYN, tell your doctor about all of your medical conditions including if you:
- have heart problems
- have kidney or liver problems
- are pregnant or plan to become pregnant. It is not known if TIKOSYN will harm your unborn baby
- are breast-feeding or plan to breast-feed. It is not known if TIKOSYN passes into your breast milk. You and your doctor should decide if you will take TIKOSYN or breast-feed. You should not do both
Especially tell your doctor if you take medicines to treat:
- heart problems
- high blood pressure
- depression or other mental problems
- allergies, or hay fever
- skin problems
Ask your doctor if you are not sure about the medicines you take. Tell your doctor about all prescription and non-prescription medicines, vitamins, dietary supplements, and any natural or herbal remedies. TIKOSYN and other medicines may affect each other, causing serious side effects. If you take TIKOSYN with certain medicines, you will be more likely to have a different type of abnormal heartbeat. See Who should not take TIKOSYN?
Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.
How should I take TIKOSYN?
- Take TIKOSYN exactly as your doctor tells you
- Do not change your TIKOSYN dose unless your doctor tells you to
- Your doctor will do tests before you start and while you take TIKOSYN
- Do not stop taking TIKOSYN until your doctor tells you to stop. If you miss a dose, just take the next dose at your regular time. Do not take 2 doses of TIKOSYN at the same time
- TIKOSYN can be taken with or without food
- If you take too much TIKOSYN, call your doctor or go to the nearest hospital emergency room right away. Take your TIKOSYN capsules with you to show to the doctor
How should I store my TIKOSYN?
- Store TIKOSYN between 59° to 86°F (15° to 30°C)
- Keep TIKOSYN away from moisture and humidity
- Keep TIKOSYN in a tightly closed container
- Keep TIKOSYN and all medicines out of the reach of children
Safety & Possible Side EffectsTop
Who should not take TIKOSYN?
Do not take TIKOSYN if you:
- have an irregular heartbeat called long QT syndrome
- have kidney problems or are on kidney dialysis
- take any of these medicines:
- cimetidine (TAGAMET®, TAGAMET HB®)
- verapamil (CALAN®, CALAN SR®, COVERA-HS®, ISOPTIN®, ISOPTIN SR®, VERELAN®, VERELAN PM®, TARKA®)
- ketoconazole (NIZORAL®, XOLEGEL®, EXTINA®)
- trimethoprim alone (PROLOPRIM®, TRIMPEX®) or the combination of trimethoprim and sulfamethoxazole (BACTRIM®, SEPTRA SULFATRIM®)
- prochlorperazine (COMPAZINE®, COMPO®)
- megestrol (MEGACE®)
- dolutegravir (TIVICAY®)
- hydrochlorothiazide alone or in combination with other medicines (such as ESIDRIX®, EZIDE®, HYDRODIURIL®, HYDRO-PAR®, MICROZIDE®, or ORETIC®)
Ask your doctor if you are not sure if any of your medicines are the kind listed above.
- are allergic to dofetilide in TIKOSYN. See Medication Guide for a complete list of ingredients in TIKOSYN
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What are the possible side effects of TIKOSYN?
TIKOSYN can cause serious side effects, including a type of abnormal heartbeat called Torsade de Pointes, which can lead to death. See What is the most important information I should know about TIKOSYN?
The most common side effects of TIKOSYN include:
- chest pain
Call your doctor right away if you have signs of electrolyte imbalance:
- severe diarrhea
- unusual sweating
- not hungry (loss of appetite)
- increased thirst (drinking more than normal)
Tell your doctor if you have any side effects that bother you or do not go away.
These are not all the possible side effects of TIKOSYN. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
About Atrial Fibrillation/Atrial FlutterTop
What is atrial fibrillation/atrial flutter, and why is it important to treat it?
In atrial fibrillation (AF)/atrial flutter (AFL), your heart doesn’t pump blood as well as normal. Blood carries oxygen to your cells. So in AF/AFL, your cells don’t get as much oxygen. This can make you feel tired. Also, when your heart doesn’t pump normally, you can have low blood pressure. This can make you pass out.
AF/AFL can lead to these and other serious conditions if not treated:
- Chronic fatigue—if you’re not getting enough blood, you may feel tired
- Heart failure—prolonged AF/AFL can weaken the heart, making heart failure more likely
- Stroke—when your heart doesn’t pump blood normally, blood can pool in your heart. This can cause clots to form. If these clots travel to the brain or the lungs, they can stop the flow of blood.
This can cause a stroke in the brain. This can also lead to a blood clot stuck in the lungs (pulmonary embolism). Either of these may lead to death.